林 誠
(はやし・まこと)
Makoto Hayashi
略歴
- 名古屋大学大学院農学研究科博士後期課程修了
- 日本学術振興会特別研究員、基礎生物学研究所助手、東北大学大学院農学研究科助教授、基礎生物学研究所助教授、同准教授を経て本学へ
植物環境細胞生化学研究室
卒業研究テーマ例
- 植物における脂質やデンプンの蓄積・分解機構とその制御
- 植物タンパク質の細胞内輸送機構に関わる遺伝子の同定と機能解明
- 植物オルガネラの機能発現制御機構
植物ペルオキシソームの機能多様性とその制御機構
オイルボディの形成機構
プロテインボディの形成機構
アミロプラストを含むプラスチドの分化制御機構
- 研究の応用領域
- 食品加工、バイオマス、バイオ燃料、種子育種
- 産官学連携で求めるパートナー
- 食品関連企業、植物育種関連企業、農業試験場、植物生理研究者
Functional diversity of plant peroxisomes and its regulation
Mechanism of oil body biogenesis
Mechanism of protein body biogenesis
Functional regulation of plastids including amyloplast
Plants chose to evolve not to move from a place where they germinated. They, therefore, need to survive by adapting the severe climate changes. Functional differentiation of plant organelles is one of the mechanisms supporting the adaptation to environmental changes. During embryogenesis and germination of seed, for example, function of plant peroxisome changes from degradation of seed-reserved lipid to photorespiration. Other organelles, such as oil body storing seed-reserved lipid, protein body storing seed storage proteins and amyloplast storing starch, are also known to change their functions drastically. I have been interested in studying functional plasticity of plant organelles and mechanisms of the regulation. These studies will provide us not only fundamental understanding of how plant adapts environmental changes, but also hints to develop technique to increase production of plant biomass.
*Fig. Mutant that lacks control of amyloplast differentiation.
Arabidopsismutantwithoutanenzyme synthesizing folic acid (right) can not control amyloplast differentiation. Therefore, it grows slower than wild-type Arabidopsis (left) in the presence of sucrose. This mutant was introduced at NHK’s TV program “Gatten”
Hayashi, M., Tanaka, M., Yamamoto, S., Nakagawa, T., Kanai, M., Anegawa, A., Ohnishi, M., Mimura, T. and Nishimura, M. (2017) Plastidial folate prevents starch biosynthesis triggered by sugar influx into non-photosynthetic plastids of Arabidopsis. Plant Cell Physiol. 58, 1328-1338.
Oikawa, K., Matsunaga, S., Mano, S., Kondo, K., Yamada, K., Hayashi M., Kagawa, T., Kadota, T., Sakamoto, W., Higashi, S., Watanabe, M., Mitsui, T., Shigemasa, A., Iino, T., Hosokawa, Y. and Nishimura, M. (2015) Physical interaction between peroxisomes and chloroplasts elucidated by in situ laser analysis. Nature Plants 1, 15035
Kanai, M., Nishimura, M. and Hayashi, M. (2010) A peroxisomal ABC transporter promotes seed germination by inducing pectin degradation under the control of ABI5. Plant J. 62, 936-947
Hayashi, M., Yagi, M., Nito, K., Kamada, T. and Nishimura, M. (2005) Dif f erential contribution of two peroxisomal protein receptors to the maintenance of peroxisomal functions in Arabidopsis. J. Biol. Chem. 280, 14829-14835.
Hayashi, M., Nito, K., Toriyama-Kato, K., Kondo, M., Yamaya, T. and Nishimura, M. (2000) AtPex14p maintains peroxisomal functions by determining protein targeting to three kinds of plant peroxisomes. EMBO J. 19, 5701-5710.